Year: 2017 | Month: August | Volume 7 | Issue 4
Phyto-Pharmacological Study and Therapeutic Efficacy of Calotropis procera (Flower) Against Theileriosis in Cattle
Abstract:
Calotropis species are common wasteland weeds, widely used as alternative therapeutic tool for the prevention or treatment of many diseases. This study was designed to evaluate the phytochemical analysis, acute toxicity studies and anti-theilerial acitivity of flowers of Calotropis procera in cattles. The results showed that the alkaloids, flavonoids, amino acids, saponin, tannins, steroids, glycosides and phenols were found in the twelve different solvent extracts of Calotropis procera. Acute toxicity studies revealed absence of toxicity symptoms upto 600 mg/kg body weight in mice. Comparative efficacy of Buparvaquone @ 2.5 mg/kg body weight and flower extract of Calotropis procera @ 0.3 mg/kg body weight was evaluated against the sub clinical theileriosis in cows. The haematological study revealed low Hb, PCV, TEC, TLC and increase in eosinophil percent in both the infected groups on day “0” (before treatment). Both the treatments improved altered levels of Hb, PCV, TEC, TLC and eosinophil percent within 21st day post treatment as compared to pre treatment values. The therapeutic study revealed that the percent efficacy of buparvaquone (100%) was higher as compared to Calotropis procera (83.67%). The study concluded that Buparvaquone and Calotropis procera found effective against sub clinical theileriosis in cows with improvement in haematological parameters.
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